Product References
Primary tumor-derived systemic nANGPTL4 inhibits metastasis.
The Journal of experimental medicine
Hübers C,Abdul Pari AA,Grieshober D,Petkov M,Schmidt A,Messmer T,Heyer CM,Schölch S,Kapel SS,Gengenbacher N,Singhal M,Schieb B,Fricke C,Will R,Remans K,Utikal JS,Reissfelder C,Schlesner M,Hodivala-Dilke KM,Kersten S,Goerdt S,Augustin HG,Felcht M
53-5381-82 was used in Flow cytometry/Cell sorting to highlight the spatial context of the proteolytic cleavage-dependent pro- and antitumorigenic functions of ANGPTL4 and identifies and validates nANGPTL4 as a novel biomarker of tumor progression and antimetastatic therapeutic agent.
Mon Jan 02 00:00:00 EST 2023
Dysregulation of interaction between LOXhigh fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection.
Theranostics
Chen Y,Zhang T,Yao F,Gao X,Li D,Fu S,Mao L,Liu F,Zhang X,Xu Y,Deng J,Li W,Fan G,Xiao C,Chen Y,Wang L,Guo W,Zhou B
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunohistochemistry
Thu Mar 10 00:00:00 EST 2022
Vascularized lymph node transplantation successfully reverses lymphedema and maintains immunity in a rat lymphedema model.
Bioengineering & translational medicine
Sakarya AH,Huang CW,Yang CY,Hsiao HY,Chang FC,Huang JJ
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity.
Nature immunology
Prados A,Onder L,Cheng HW,Mörbe U,Lütge M,Gil-Cruz C,Perez-Shibayama C,Koliaraki V,Ludewig B,Kollias G
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9.
Journal of cell science
de Winde CM,Makris S,Millward LJ,Cantoral-Rebordinos JA,Benjamin AC,Martínez VG,Acton SE
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Thu Jul 15 00:00:00 EDT 2021
CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice.
Theranostics
Tang C,Wang L,Sheng Y,Zheng Z,Xie Z,Wu F,You T,Ren L,Xia L,Ruan C,Zhu L
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2022
CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice.
Theranostics
Tang C,Wang L,Sheng Y,Zheng Z,Xie Z,Wu F,You T,Ren L,Xia L,Ruan C,Zhu L
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2022
CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice.
Theranostics
Tang C,Wang L,Sheng Y,Zheng Z,Xie Z,Wu F,You T,Ren L,Xia L,Ruan C,Zhu L
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2022
Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes.
PLoS biology
Fujimoto N,He Y,D'Addio M,Tacconi C,Detmar M,Dieterich LC
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth.
eLife
Thacker VV,Dhar N,Sharma K,Barrile R,Karalis K,McKinney JD
53-5381-82 was used in Immunocytochemistry to probe the direct role of pulmonary surfactant in early infection.
Tue Nov 24 00:00:00 EST 2020
A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth.
eLife
Thacker VV,Dhar N,Sharma K,Barrile R,Karalis K,McKinney JD
53-5381-82 was used in Immunocytochemistry to probe the direct role of pulmonary surfactant in early infection.
Tue Nov 24 00:00:00 EST 2020
Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.
Immunity
Camara A,Cordeiro OG,Alloush F,Sponsel J,Chypre M,Onder L,Asano K,Tanaka M,Yagita H,Ludewig B,Flacher V,Mueller CG
53-5381 was used in Flow cytometry/Cell sorting to demonstrate that mesenchymal stromal cells created a niche environment with LECs for specialized macrophages to take up residence, complete their differentiation program, and fulfill their immune function.
Tue Jun 18 00:00:00 EDT 2019
Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury.
JCI insight
Riemondy KA,Jansing NL,Jiang P,Redente EF,Gillen AE,Fu R,Miller AJ,Spence JR,Gerber AN,Hesselberth JR,Zemans RL
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Tue Mar 26 00:00:00 EDT 2019
Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease.
eLife
Jafree DJ,Moulding D,Kolatsi-Joannou M,Perretta Tejedor N,Price KL,Milmoe NJ,Walsh CL,Correra RM,Winyard PJ,Harris PC,Ruhrberg C,Walker-Samuel S,Riley PR,Woolf AS,Scambler PJ,Long DA
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunocytochemistry
Fri Dec 06 00:00:00 EST 2019
Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability.
International journal of cancer
Dieterich LC,Kapaklikaya K,Cetintas T,Proulx ST,Commerford CD,Ikenberg K,Bachmann SB,Scholl J,Detmar M
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Fri Nov 15 00:00:00 EST 2019
Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells.
Nature communications
Hsu M,Rayasam A,Kijak JA,Choi YH,Harding JS,Marcus SA,Karpus WJ,Sandor M,Fabry Z
53-5381 was used in Immunohistochemistry to show that increased lymphangiogenesis near the cribriform plate can contribute to the management of neuroinflammation-induced fluid accumulation and immune surveillance.
Wed Jan 16 00:00:00 EST 2019
Podoplanin is an important stromal prognostic marker in perihilar cholangiocarcinoma.
Oncology letters
Obulkasim H,Shi X,Wang J,Li J,Dai B,Wu P,Wang S,Wang X,Ding Y
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers.
Developmental dynamics : an official publication of the American Association of Anatomists
Ogawa T,Li Y,Lua I,Hartner A,Asahina K
53-5381 was used in Flow cytometry/Cell sorting to suggest that ITGA8+ mesenchymal cells maintain the phenotype of hepatoblast in liver development.
Fri Jun 01 00:00:00 EDT 2018
The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.
eLife
Schlereth K,Weichenhan D,Bauer T,Heumann T,Giannakouri E,Lipka D,Jaeger S,Schlesner M,Aloy P,Eils R,Plass C,Augustin HG
53-5381 was used in Flow cytometry/Cell sorting to establish the transcriptional and epigenetic landscape of vascular quiescence in the continuous lung endothelium.
Fri May 11 00:00:00 EDT 2018
ABCG1 regulates pulmonary surfactant metabolism in mice and men.
Journal of lipid research
de Aguiar Vallim TQ,Lee E,Merriott DJ,Goulbourne CN,Cheng J,Cheng A,Gonen A,Allen RM,Palladino END,Ford DA,Wang T,Baldán Á,Tarling EJ
53-5381 was used in Flow cytometry to establish a critical role for T2 cell ABCG1 in controlling surfactant and overall lipid homeostasis in the lung.
Mon May 01 00:00:00 EDT 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Geldanamycin Reduces Acute Respiratory Distress Syndrome and Promotes the Survival of Mice Infected with the Highly Virulent H5N1 Influenza Virus.
Frontiers in cellular and infection microbiology
Wang C,Liu P,Luo J,Ding H,Gao Y,Sun L,Luo F,Liu X,He H
53-5381 was used in Flow cytometry/Cell sorting to show geldanamycin plays an important role in attenuating virus infection-induced acute lung injury/acute respiratory distress syndrome by reducing the host's inflammatory responses.
Mon Feb 26 00:00:00 EST 2018
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.
Nature medicine
Cloonan SM,Glass K,Laucho-Contreras ME,Bhashyam AR,Cervo M,Pabón MA,Konrad C,Polverino F,Siempos II,Perez E,Mizumura K,Ghosh MC,Parameswaran H,Williams NC,Rooney KT,Chen ZH,Goldklang MP,Yuan GC,Moore SC,Demeo DL,Rouault TA,D'Armiento JM,Schon EA,Manfredi G,Quackenbush J,Mahmood A,Silverman EK,Owen CA,Choi AM
53-5381 was used in Immunofluorescence to demonstrate that mice deficient in Irp2 were protected from cigarette smoke-induced experimental pulmonary disease.
Mon Feb 01 00:00:00 EST 2016
Stem cell function and stress response are controlled by protein synthesis.
Nature
Blanco S,Bandiera R,Popis M,Hussain S,Lombard P,Aleksic J,Sajini A,Tanna H,Cortés-Garrido R,Gkatza N,Dietmann S,Frye M
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Thu Jun 16 00:00:00 EDT 2016
Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers.
Journal of hepatology
Lua I,Li Y,Zagory JA,Wang KS,French SW,Sévigny J,Asahina K
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunohistochemistry
Sun May 01 00:00:00 EDT 2016
Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers.
Journal of hepatology
Lua I,Li Y,Zagory JA,Wang KS,French SW,Sévigny J,Asahina K
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunohistochemistry
Sun May 01 00:00:00 EDT 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer.
PloS one
Kitamura J,Uemura M,Kurozumi M,Sonobe M,Manabe T,Hiai H,Date H,Kinoshita K
Mon Mar 30 00:00:00 EDT 2015
BILL-cadherin/cadherin-17 contributes to the survival of memory B cells.
PloS one
Funakoshi S,Shimizu T,Numata O,Ato M,Melchers F,Ohnishi K
53-5381 was used in Flow cytometry/Cell sorting to study how CDH17 plays a role in the long-term survival of memory B cells via an 'MBC niche'.
Wed Sep 16 00:00:00 EDT 2015
MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.
Nature communications
Pratama A,Srivastava M,Williams NJ,Papa I,Lee SK,Dinh XT,Hutloff A,Jordan MA,Zhao JL,Casellas R,Athanasopoulos V,Vinuesa CG
53-5381 was used in Flow cytometry/Cell sorting to study how miR-146a emerges as a post-transcriptional brake to limit Tfh cells and GC responses.
Fri Mar 06 00:00:00 EST 2015
Alveolar progenitor and stem cells in lung development, renewal and cancer.
Nature
Desai TJ,Brownfield DG,Krasnow MA
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Thu Mar 13 00:00:00 EDT 2014
Dendritic cells control fibroblastic reticular network tension and lymph node expansion.
Nature
Acton SE,Farrugia AJ,Astarita JL,Mourão-Sá D,Jenkins RP,Nye E,Hooper S,van Blijswijk J,Rogers NC,Snelgrove KJ,Rosewell I,Moita LF,Stamp G,Turley SJ,Sahai E,Reis e Sousa C
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Thu Oct 23 00:00:00 EDT 2014
Dendritic cells control fibroblastic reticular network tension and lymph node expansion.
Nature
Acton SE,Farrugia AJ,Astarita JL,Mourão-Sá D,Jenkins RP,Nye E,Hooper S,van Blijswijk J,Rogers NC,Snelgrove KJ,Rosewell I,Moita LF,Stamp G,Turley SJ,Sahai E,Reis e Sousa C
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Thu Oct 23 00:00:00 EDT 2014
Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury.
Hepatology (Baltimore, Md.)
Lua I,James D,Wang J,Wang KS,Asahina K
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Tue Jul 01 00:00:00 EDT 2014
Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major.
PLoS pathogens
Ballet R,Emre Y,Jemelin S,Charmoy M,Tacchini-Cottier F,Imhof BA
53-5381 was used in Flow cytometry/Cell sorting to illustrate a key role for the vascular adhesion molecule JAM-C in controlling leukocyte migration and subsequent immune events in response to pathogen infections.
Mon Dec 01 00:00:00 EST 2014
C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.
Clinical and experimental immunology
Ruseva MM,Takahashi M,Fujita T,Pickering MC
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Tue Apr 01 00:00:00 EDT 2014
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection.
Cell
Teijaro JR,Walsh KB,Cahalan S,Fremgen DM,Roberts E,Scott F,Martinborough E,Peach R,Oldstone MB,Rosen H
53-5381 was used in Flow cytometry/Cell sorting to elucidate cellular and signalling mechanisms that are important in initiating cytokine storm.
Fri Sep 16 00:00:00 EDT 2011
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology (Baltimore, Md.)
Asahina K,Tsai SY,Li P,Ishii M,Maxson RE,Sucov HM,Tsukamoto H
Published figure using Podoplanin monoclonal antibody (Product # 53-5381-82) in Immunofluorescence
Sun Mar 01 00:00:00 EST 2009