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Invitrogen
Polysialic acid Recombinant Mouse Monoclonal Antibody (735)
Product Details
MA5-51822
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
735
Immunogen
Homopolymers of alpha2,8-linked sialic acid of Escherichia coli K1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3250514
Product Specific Information
Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of alpha 2,8-linked sialic acid of Escherichia coli K1.
Target Information
Polysialic acid is a glycan polymer composed of repeating units of the monosaccharide sialic acid. It consists of a linear chain of alpha-2,8-linked sialic acid residues that can extend up to 200 units in length. This negatively charged molecule is commonly present in the cell membranes of various organisms, including bacteria and animals, and plays a crucial role in regulating cell adhesion, migration, and neural development. Polysialic acid is also being explored for its potential therapeutic applications in the treatment of certain cancers and neurological disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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