|Tested species reactivity||Mouse, Rat, Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from C-terminus of human progesterone receptor protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Western Blot (WB)||5-10 µg/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA5-16435 targets Progesterone Receptor in WB applications and shows reactivity with mouse, Rat, and Human samples.
The PA5-16435 immunogen is a synthetic peptide derived from C-terminus of human progesterone receptor protein.
Human PgR exists in two forms: 116kDa (B-form) and 81kDa (A-form). It acts as ligand activated transcription factor to regulate expression of the target genes. Null mutation in PgR gene leads to pleiotrophic reproductive abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Effects of progesterone on the content of CCR5 and CXCR4 coreceptors in PBMCs of seropositive and exposed but uninfected Mexican women to HIV-1.
PA5-16435 was used in western blot to study the effects of progesterone on PBMC CCR4 and CXCR4 levels in HIV-1 infected and HIV-1-exposed but uninfected Mexican women
|Cabrera-Muñoz E,Fuentes-Romero LL,Zamora-Chávez J,Camacho-Arroyo I,Soto-Ramírez LE||The Journal of steroid biochemistry and molecular biology (132:66)||2012|