|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human Protein C purified from the supernatant of thrombin activated platelets.|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17645 targets Protein C/APC in ELISA and WB applications and shows reactivity with Human samples.
The MA5-17645 immunogen is human Protein C purified from the supernatant of thrombin activated platelets.
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; prepro-protein C; PROC; protein C (inactivator of coagulation factors Va and VIIIa); type I protein C; Vitamin K-dependent protein C
Gene Aliases: APC; PC; PROC; PROC1; THPH3; THPH4
UniProt ID: (Human) P04070
Entrez Gene ID: (Human) 5624
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