|Immunoprecipitation (IP)||10-15 µg/ml|
|Western Blot (WB)||5-10 µg/ml|
|Tested Species reactivity||Bovine, Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||C-terminal peptide (amino acids 318-327) of PP1 beta catalytic subunit|
|Purification||Ammonium sulfate precipitation|
|Contains||0.08% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody will not cross-react with other PP1 isoforms.
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein Li 80p; MGC21657; PP-1B; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, delta isoform; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase-1a; serine/threonine protein phosphatase PP1-beta catalytic subunit; Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Gene Aliases: 1200010B19; BOS_11856; HEL-S-80p; PP-1B; PP1B; PP1beta; PPP1CB; PPP1CD
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