|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Protein purified from Human plasma|
|Storage buffer||HEPES with 0.15M NaCl, 0.01% BSA, 50% glycerol|
|Contains||0.03% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||0.5 mg/ml|
A suggested positive control for this product is human plasma.
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
coagulation factor II (thrombin); prepro-coagulation factor II; prothrombin B-chain; PT; serine protease
F2; PT; RPRGL2; THPH1