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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide comprising residues 351-366 of the human P2Y2 protein.|
|Purification||Antigen affinity chromatography|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: human brain lysate and rat dorsal root ganglion, antigen standard for P2RY2 (transient overexpression lysate).
P2Y2 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. P2Y2 is also a morphogen receptor that potentiates neurotrophin signaling in neuronal development and regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ATP receptor; P2RY2; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; P2U1; P2Y ATP receptor 2; P2Y purinoceptor 2; purinergic receptor P2Y, G-protein coupled, 2; purinoceptor P2Y2
HP2U; P2RU1; P2RY2; P2U; P2U1; P2UR; P2Y2; P2Y2R