Invitrogen

RAB9 Recombinant Rabbit Monoclonal Antibody (ARC0332)

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RAB9 Antibody in Western Blot (WB) — Western Blot analysis of RAB9 performed on various cell lines using a RAB9 monoclonal antibody (Product # MA5-35602) at a dilution of 1:1,000. An HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was applied at a dilution of 1:10,000.

Product Details

MA5-35602

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Recombinant Monoclonal
Type	Antibody
Clone	ARC0332
Immunogen	A synthesized peptide derived from human RAB9A
Conjugate	Unconjugated
Form	Liquid
Concentration	1.25 mg/mL
Purification	Protein A
Storage buffer	PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2849502

Target Information

Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell. Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN). By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components. It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.