This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
MA1-23271 detects Rad51 in human and chicken samples.
MA1-23271 has been successfully used in immunofluorescence, immunoprecipitation, IHC-P, and Western blot procedures. A suggested positive control for this product is T24.
The MA1-23271 immunogen is full length Rad51 protein (amino acids 1-338) expressed in E. coli.
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51 homolog 1; homolog to S.cerevisiae; HRAD51; HsRAD51; HsT16930; RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RECA; RecA, E. coli, homolog of; RecA-like protein; recombination protein A
Gene Aliases: AV304093; BRCC5; FANCR; HRAD51; HsRad51; HsT16930; MRMV2; RAD51; RAD51A; RECA