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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human RAG1 (amino acids: 818-868) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17163 targets RAG1 in pep-ELISA and WB applications and shows reactivity with Human samples.
The MA5-17163 immunogen is purified recombinant fragment of human RAG1 (amino acids: 818-868) expressed in E. Coli.
MA5-17163 detects RAG1 which has a predicted molecular weight of approximately 119kDa.
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
RAG-1; recombination activating protein 1; RING finger protein 74; V(D)J recombination-activating protein 1
RAG-1; RAG1; RNF74