AGER encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6.
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Protein Aliases: advanced glycation end-products receptor; Advanced glycosylation end product-specific receptor; RAGE; RAGE isoform NtRAGE-delta; RAGE isoform sRAGE-delta; receptor for advanced glycation end-products variant 20; Receptor for advanced glycosylation end products
Gene Aliases: AGER; RAGE; SCARJ1