This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human RAGE/AGER.
The receptor for advanced glycation endproducts (RAGE) is a member of the Immunoglobin superfamily of cell surface markers. This protein is able to interact with many molecules including: advanced glycation endproducts (AGE), amphoterin, and ligands. Research has shown that the accumulation of RAGE ligands in the biological system (endothelium mononuclear phagocytes, neurons and smooth muscle cells) can lead to destructive tissue diseases such as diabetic retinopathy, amyloidoses, tumors and inflammation disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Advanced glycosylation end product-specific receptor; RAGE isoform NtRAGE-delta; RAGE isoform sRAGE-delta; Receptor for Advanced Glycation End Products; receptor for advanced glycation end-products variant 20; Receptor for advanced glycosylation end products; Receptor for advanced glycosylation end-pro; Soluble form of receptor for advanced glycation endproducts
Gene Aliases: AGER; RAGE; SCARJ1
UniProt ID: (Human) Q15109
Entrez Gene ID: (Human) 177