MA1-20302 detects RANK in mouse samples.
MA1-20302 has been successfully used in ELISA, FACS and immunoprecipitation procedures.
The MA1-20302 immunogen corresponds to RANK-Fc mouse fusion protein.
RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.
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Protein Aliases: CD265; Ly109; mRANK; ODFR; OFE; Osteoclast differentiation factor receptor; Rank; receptor activator of NF-kappaB; Receptor activator of NF-KB; TRANCE-R; Tumor necrosis factor receptor superfamily member 11A
Gene Aliases: Ly109; mRANK; ODFR; OFE; Rank; Tnfrsf11a; TRANCE-R
UniProt ID: (Mouse) O35305
Entrez Gene ID: (Mouse) 21934