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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Human recombinant RANTES.|
|Storage buffer||PBS, pH 7.3, with 5mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Purity is >95% by SDS-PAGE.
This product is recommended as a detection antibody in Sandwich ELISA applications.
This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
beta-chemokine RANTES; chemokine (C-C motif) ligand 5; D17S136E; eoCP; eosinophil chemotactic cytokine; MGC17164; regulated upon activation, normally T-expressed, and presumably secreted; SCYA5; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; t cell-specific protein P228; T-cell specific protein p288; TCP228
CCL5; D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228