Immunogen sequence: TQSSASLAAS YAAQQHPQAA ASYRGQPGNA YDGAGQPSAA YLSMSQGAVA NANSTPPPYE RTRLSPPRAS YDDPYKKAVA MSKRYGSDRR LAELSDYRRL SESQLSFRRS PTKSSLDYRR LPDAHSDYAR
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COAA; coactivator activator; Paraspeckle protein 2; PSP2; RNA-binding motif protein 14; RNA-binding protein 14; RRM-containing coactivator activator/modulator; synaptotagmin interacting protein; Synaptotagmin-interacting protein; SYT-interacting protein; SYTIP1; TMEM137; transmembrane protein 137
Gene Aliases: 1300007E16Rik; COAA; p16; p16K; PSP2; RBM14; SIP; Sytip; SYTIP1; TMEM137