MA5-15838 targets RBP4 in FACS, IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15838 immunogen is purified recombinant fragment of human RBP expressed in E. Coli.
MA5-15838 detects RBP4 which has a predicted molecular weight of approximately 23kDa.
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Plasma retinol-binding protein; Plasma retinol-binding protein(1-176); Plasma retinol-binding protein(1-179); Plasma retinol-binding protein(1-181); Plasma retinol-binding protein(1-182); PRBP; RBP; retinol; retinol binding; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial
Gene Aliases: MCOPCB10; PRO2222; RBP4; RDCCAS
UniProt ID: (Human) P02753
Entrez Gene ID: (Human) 5950
Molecular Function: transfer/carrier protein