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REN Antibody (TA807104) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY REN (RC208382, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-REN. (1:5. Positive lysates LY424660 (100 µg) and LC424660 (20 µg) can be purchased separately from OriGene.
Product Details
TA807104
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4A3
Immunogen
Human recombinant protein fragment corresponding to amino acids 131-406 of human REN produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: angiotensin-forming enzyme; Angiotensinogenase; EC 3.4.23; EC 3.4.23.15; FLJ10761; Renin; renin precursor, renal
Gene Aliases: HNFJ2; REN
UniProt ID: (Human) P00797
Entrez Gene ID: (Human) 5972
kidney development
mesonephros development
angiotensin maturation
renin-angiotensin regulation of aldosterone production
proteolysis
regulation of blood pressure
male gonad development
hormone-mediated signaling pathway
protein catabolic process
response to lipopolysaccharide
cellular response to drug
response to immobilization stress
drinking behavior
regulation of MAPK cascade
cell maturation
beta-amyloid metabolic process
response to cAMP
response to cGMP
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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