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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Recombinant protein encoding the full-length p37 subunit ofhuman RFC purified from E. coli.|
|Storage buffer||whole serum diluted in PBS, pH 7.4|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23323 detects replication factor C (RFC) p37 in human samples.
PA1-23323 has been successfully used in Western blot procedures.
The PA1-23323 immunogen is a recombinant protein encoding the full-length p37 subunit ofhuman RFC purified from E. coli..
Human Replication Factor C (RFC) is a hetero-pentameric protein consisting of the p140, p40, p38, p37 and p36 subunits. RFC functions in the loading of the DNA polymerase delta processivity factor (PCNA, Proliferating Cell nuclear Antigen) onto a primed DNA template during DNA synthesis and repair. RFC may also participate in the DNA damage checkpoint response with a PCNA-like hetero-trimer consisting of Hus 1, Rad 1 and Rad 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A1 37 kDa subunit; activator 1 37 kDa subunit; activator 1 subunit 4; replication factor C (activator 1) 4, 37kDa; replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC 37 kDa subunit; RFC p37
A1; RFC37; RFC4