Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
Protein Aliases: CARP-2; Caspase regulator CARP2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin-protein ligase rififylin; Fring; FYVE-RING finger protein SAKURA; rififylin; ring finger and FYVE like domain containing protein; ring finger and FYVE-like domain containing 1; RING finger and FYVE-like domain-containing protein 1; RING finger protein 189; RING finger protein 34-like; RING finger protein SAKURA; RING-type E3 ubiquitin transferase rififylin
Gene Aliases: 1700051E09Rik; 4930516L10Rik; BG080975; CARP-2; CARP2; FRING; RFFL; RIFIFYLIN; RNF189; RNF34L
Molecular Function: ubiquitin-protein ligase