|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from ligand-binding domain of human ROR Alpha.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The retinoic acid receptor-related orphan receptor alpha (ROR alpha), also known as RZRa, is a member of structurally related, nuclear receptor superfamily. To date, ROR alpha, beta, and gamma subtypes have been discovered and within the ROR alpha group there are ROR alpha 1, 2, 3, and 4. ROR isotypes have been shown to differ in only their amino terminus. Research has shown that these proteins are key in regulation of many physiological processes such as cell growth and differentiation. ROR alpha is also critical for proper cerebellar development, modulation of gene expression in response to hypoxic stress, and migratory capacities of cancer cells. The corresponding gene for the ROR alpha is NR1F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.