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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to the C-Terminus of RPA p11.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA3-955 detects RPA p11 in human cells.
PA3-955 has been successfully used in Western blotting procedures. By Western blot it detects a ~11 kDa protein representing RPA p11.
The PA3-955 immunogen is a synthetic peptide conjugated to the 20 amino acids of the RPA p11C-terminus.
RPA p11 is a subunit of replication protein A, also known as Human single-stranded DNA-binding protein (HSSB). P11 and p34 are thought to form the base for the complex before p70 is added to the complex. Disruption of the p11 subunit blocks replication, due to the lack of formation of the entire HSSB complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
HSSB; Replication Protein A