MA5-17167 targets RPL18A in IHC and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17167 immunogen is purified recombinant fragment of human RPL18A (amino acids: 50-176) expressed in E. Coli.
MA5-17167 detects RPL18A which has a predicted molecular weight of approximately 20.8kDa.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.
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Protein Aliases: 60S ribosomal protein L18a; Large ribosomal subunit protein eL20; ribosomal protein L18a-like protein
Gene Aliases: 2510019J09Rik; L18A; RPL18A