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OriGene
RRM2 Monoclonal Antibody (OTI1F2), TrueMAB™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CF810548
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI1F2
Immunogen
Full length human recombinant protein of human RRM2 produced in HEK293T.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ribonucleoside-diphosphate reductase M2 chain; Ribonucleotide reductase 2; ribonucleotide reductase M2 polypeptide; ribonucleotide reductase small chain; ribonucleotide reductase small subunit; ribonucleotide reductase subunit M2; RRR2M; uncharacterized protein C2orf48; unnamed protein product
Gene Aliases: C2orf48; R2; RR2; RR2M
UniProt ID: (Human) P31350, (Rat) Q4KLN6, (Mouse) P11157
Entrez Gene ID: (Human) 6241, (Rat) 362720, (Mouse) 20135
pyrimidine nucleobase metabolic process
dTMP biosynthetic process
DNA repair
positive regulation of cell proliferation
ribonucleoside diphosphate metabolic process
deoxyribonucleotide metabolic process
deoxyribonucleotide biosynthetic process
2'-deoxyribonucleotide biosynthetic process
protein heterotetramerization
nucleobase-containing small molecule metabolic process
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of mitotic cell cycle phase transition
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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