Invitrogen

RSK1 Monoclonal Antibody (257R21)

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RSK1 Antibody in Western Blot (WB) — Western blot analysis of RSK1 using a monoclonal antibody (Product # AHO1472).

Product Details

Tested Applications

Dilution

Western Blot (WB)

Assay Dependent

Published Applications

Miscellaneous PubMed (MISC)

See 1 publication below

Western Blot (WB)

See 1 publication below

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host / Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

257R21

Immunogen

Recombinant fragment of human RSK1 expressed in E. coli.

Conjugate

Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 1% BSA

Contains

0.1% sodium azide

Storage conditions

-20°C

RRID

AB_2536341

Target Information

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 90 kDa ribosomal protein S6 kinase 1; 90kD; dJ590P13.1 (ribosomal protein S6 kinase; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; MAPKAPK1A; p90-RSK 1; p90RSK1; p90S6K; polypeptide 1); pp90RSK1; r; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; Ribosomal S6 kinase 1; RSK; RSK-1; RSK1; S6 protein kinase (Rsk-1); S6K-alpha 1; S6K-alpha-1

Gene Aliases: HU-1; Mapkapk-1a; MAPKAPK1A; p90-Rsk1; p90Rsk; p90Rsk1; p90S6K; RPS6KA1; RSK; Rsk-1; RSK1; S6K-alpha-1

UniProt ID: (Human) Q15418, (Rat) Q63531, (Mouse) P18653

Entrez Gene ID: (Human) 6195, (Rat) 81771, (Mouse) 20111

Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase