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      RSK1 Monoclonal Antibody (257R21)

      See 23 other RSK1 antibodies ›
      RSK1 Monoclonal Antibody for Western Blot

      Catalog#: AHO1472 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      AHO1472 100 µg
      304.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

      Anti-Mouse Secondary Antibodies (597)
      Alexa Fluor® Anti-Mouse Secondary Antibodies (122)
      HRP Anti-Mouse Secondary Antibodies (86)

      Product Details

      References

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human, Mouse, Rat
      Published species reactivity Human
      Host / Isotype Mouse / IgG1, kappa
      Class Monoclonal
      Type Antibody
      Clone 257R21
      Immunogen Recombinant fragment of human RSK1 expressed in E. coli.
      Conjugate Unconjugated
      Form Liquid
      Purification Affinity chromatography
      Storage buffer PBS, pH 7.2, with 1% BSA
      Contains 0.1% sodium azide
      Storage Conditions -20°C
      Tested Applications Dilution *
      Western Blot (WB) Assay Dependent

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Published Applications
      Miscellaneous PubMed (MISC) See 1 publications below
      Western Blot (WB) See 1 publications below

      Background/Target Information

      This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      References

      Miscellaneous PubMed

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Human
      		Not Cited
      		A plate-based assay to measure cellular ERK substrate phosphorylation: utility for drug discovery of the MAPK-signaling cascade. Ramaswamy S,Yen I,Sideris S,Malek S,Heise CE Assay and drug development technologies (8:497) 2010

      Western Blot

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Human 1:1000 A plate-based assay to measure cellular ERK substrate phosphorylation: utility for drug discovery of the MAPK-signaling cascade. Ramaswamy S,Yen I,Sideris S,Malek S,Heise CE Assay and drug development technologies (8:497) 2010

      Bioinformatics

      Protein Aliases:

      90 kDa ribosomal protein S6 kinase 1; 90kD; dJ590P13.1 (ribosomal protein S6 kinase; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; MAPKAPK1A; p90-RSK 1; p90RSK1; p90S6K; polypeptide 1); pp90RSK1; r; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; Ribosomal S6 kinase 1; RSK; RSK-1; RSK1; S6 protein kinase (Rsk-1); S6K-alpha 1; S6K-alpha-1

      Gene Aliases:

      HU-1; Mapkapk-1a; MAPKAPK1A; p90-Rsk1; p90Rsk; p90Rsk1; p90S6K; RPS6KA1; RSK; Rsk-1; RSK1; S6K-alpha-1

      UniProt ID:

      (Human) Q15418, (Rat) Q63531, (Mouse) P18653

      Entrez Gene ID:

      (Human) 6195, (Rat) 81771, (Mouse) 20111

      Molecular Function:

      annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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