MA5-15538 targets RTN3 in IF applications and shows reactivity with Human samples.
The MA5-15538 immunogen is purified recombinant fragment of RTN3 expressed in E. Coli.
MA5-15538 detects RTN3 which has a predicted molecular weight of approximately 113kDa.
RTN3 is a member of reticulons, which are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified. Multiple promoters rather than alternative splicing of internal exons seem to be involved in this diversity.
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Protein Aliases: ASY interacting protein; ASYIP; HAP; Homolog of ASY protein; Neuroendocrine-specific protein-like 2; Neuroendocrine-specific protein-like II; NSP-like protein 2; NSP-like protein II; NSPL2; NSPLII; Reticulon-3; RTN3; RTN3-A1
Gene Aliases: ASYIP; HAP; NSPL2; NSPLII; RTN3; RTN3-A1
UniProt ID: (Human) O95197
Entrez Gene ID: (Human) 10313
Molecular Function: membrane traffic protein