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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 14 amino acid peptide from 2nd cytoplasmic domain of human RXFP2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||26 - 130 µg/ml|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Horse (100%) Monkey, Panda (93%) Dog, Pig, Xenopus (86%).
The activity of this relaxin receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP and may also be a receptor for Leydig insulin-like peptide. Expressed in embryonic and adult gonads of males and females, as well in male gubernarculum and in brain. Not detected in kidney, spleen and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
G protein coupled receptor affecting testicular descent; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; GPR106; GREAT; INSL3R; leucine-rich repeat-containing G protein-coupled receptor 8; leucine-rich repeat-containing G-protein coupled receptor 8; LGR8; LGR8.1; relaxin family peptide receptor 2; relaxin/insulin-like family peptide receptor 2; RXFP2; RXFPR2
GPR106; GREAT; INSL3R; LGR8; LGR8.1; RXFP2; RXFPR2