|Tested species reactivity||Human, Rat|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Microsomal fraction of human renal cortical tissue homogenate|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4 µg/ml|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-13365 targets Renal Cell Carcinoma Marker in IHC (P) and WB applications and shows reactivity with Human and Rat samples.
The MA5-13365 immunogen is microsomal fraction of human renal cortical tissue homogenate.
In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Of other normal tissues examined, the gp200 is also localized along the luminal surfaces of breast lobules and ducts, the luminal surface of the epididymal tubular epithelium, within the cytoplasm of parathyroid parenchymal cells, and focally within the colloid of thyroid follicles. Thirty-one other normal tissues do not express similar or cross-reacting antigens. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A reference image-based method for optimization of clinical immunohistochemistry.
MA5-13365 was used in immunohistochemistry to describe a new method for immunohistochemistry optimization
|Kap M,Lam KH,Ewing-Graham P,Riegman P||Histopathology (67:193)||2015|
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
MA5-13365 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression
|Yin WH,Li J,Chan JK||Diagnostic pathology (7:null)||2012|
Mucinous tubular and spindle cell carcinoma of kidney and problems in diagnosis.
MA5-13365 was used in immunohistochemistry to study problems in diagnosing mucinous tubular and spindle cell carcinoma of kidney
|Sarsik B,S¿m¿¿r A,Karaarslan S,Sen S||Turk patoloji dergisi (27:116)||2011|
Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary.
MA5-13365 was used in immunohistochemistry to study the clinical value of gene expression profiling of metastatic adenocarcinomas of unknown primary
|Horlings HM,van Laar RK,Kerst JM,Helgason HH,Wesseling J,van der Hoeven JJ,Warmoes MO,Floore A,Witteveen A,Lahti-Domenici J,Glas AM,Van't Veer LJ,de Jong D||Journal of clinical oncology : official journal of the American Society of Clinical Oncology (26:4435)||2008|
Clinicopathological characteristics of kidney mucinous tubular and spindle cell carcinoma.
MA5-13365 was used in immunohistochemistry - paraffin section to describe the clinicopathologically features of two cases of kidney mucinous tubular and spindle cell carcinoma
|Chen Q,Gu Y,Liu B||International journal of clinical and experimental pathology (8:1007)||2015|