PA5-34827 targets Renin in ICC, IF, and WB applications and shows reactivity with Human samples.
The PA5-34827 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 302 of Renin (Uniprot ID#P00797).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: angiotensin-forming enzyme; Angiotensinogenase; HNFJ2; renal; Renin; renin precursor; renin precursor, renal
Gene Aliases: HNFJ2; REN
UniProt ID: (Human) P00797
Entrez Gene ID: (Human) 5972