|Tested species reactivity||Virus|
|Host / Isotype||Mouse / IgG1, IgG2a|
|Clone||4 clone blend|
|Immunogen||RSV strain A2|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:50-1:400|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:400|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. This antibody can be used with formalin-fixed, paraffin-embedded RSV-infected lung tissue in immunohistochemical applications. For IF, use acetone-fixed HeLa cells infected with RSV-A2.
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.