|Tested species reactivity||Goat, Human, Mouse, Non-human primate, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human plasma RBP.|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
MA1-35782 only detects methylated RBP. In order to detect RBP, a methylation step of the antigen must be applied.
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Transforming growth factor-beta and substrate stiffness regulate portal fibroblast activation in culture.
MA1-35782 was used in immunohistochemistry to investigate the influence of tumor growth factor beta on portal fibroblast activation
|Li Z,Dranoff JA,Chan EP,Uemura M,Sévigny J,Wells RG||Hepatology (Baltimore, Md.) (46:1246)||2007|
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.
MA1-35782 was used in immunohistochemistry to study the gene expression profiles of experimentally induced rat mammary gland carcinomas using cDNA microarray analysis
|Shan L,He M,Yu M,Qiu C,Lee NH,Liu ET,Snyderwine EG||Carcinogenesis (23:1561)||2002|