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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 37 and 222 of Human RhoGAP|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31330 targets RhoGAP in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31330 immunogen is recombinant protein fragment corresponding to a region within amino acids 37 and 222 of Human RhoGAP.
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CDC42 GTPase-activating protein; GFI2; growth factor independent 2; GTPase-activating protein rhoGAP; GTPase-activating protein rhoOGAP; GTPase-activating protein, Rho, 1; p100 RasGAP-associated p105 protein; p105 RhoGAP; p190BRhoGAP; p50-RhoGAP; Rho GTPase-activating protein 1; rho GTPase-activating protein 5; Rho-related small GTPase protein activator; Rho-type GTPase-activating protein 1; rho-type GTPase-activating protein 5; RhoGAP5
ARHGAP1; CDC42GAP; p50rhoGAP; RHOGAP; RHOGAP1