|Tested species reactivity||Bovine, Dog, Horse, Cat, Human, Mouse, Rat|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified recombinant human S100 A6 monomer expressed in E. coli|
|Storage buffer||whole serum diluted in PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200-1:400|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
PA5-16590 targets S100 A6 in IHC (P) applications and shows reactivity with Bovine, Canine, Equine, Feline, Human, mouse, and Rat samples.
The PA5-16590 immunogen is purified recombinant human S100 A6 monomer expressed in E. coli.
S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI imaging.
PA5-16590 was used in immunohistochemistry to characterize protein biomarkers of metastasis in papillary thyroid carcinoma
|Nipp M,Elsner M,Balluff B,Meding S,Sarioglu H,Ueffing M,Rauser S,Unger K,Höfler H,Walch A,Zitzelsberger H||Journal of molecular medicine (Berlin, Germany) (90:163)||2012|