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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified S100 protein from human brain.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-23052 detects S100 beta in Human samples.
MA1-23052 has been successfully used in Sandwhich ELISA and Western Blot procedures.
MA1-23052 immunogen corresponds to Purified S100 protein from human brain.
This protein is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
NEF; S-100 calcium-binding protein, beta chain; S-100 protein subunit beta; S100; S100 calcium-binding protein, beta (neural); S100beta
NEF; S100; S100-B; S100B; S100beta