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          • Primary Antibodies ›
          • Calprotectin Antibodies

          NeoBiotechnologies

          S100A9 + Calprotectin (S100A8/A9 Complex) Recombinant Rabbit Monoclonal Antibody (MAC3157R)

          View all (98) Calprotectin antibodies

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          Cite S100A9 + Calprotectin (S100A8/A9 Complex) Recombinant Rabbit Monoclonal Antibody (MAC3157R)

          • Antibody Testing Data (3)
          S100A9 + Calprotectin (S100A8/A9 Complex) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          S100A9 + Calprotectin (S100A8/A9 Complex) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 3

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          S100A9 + Calprotectin (S100A8/A9 Complex) Antibody (6279-RBM5-P1ABX) in IHC (P)

          Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human tonsil using S100A9 + Calprotectin (S100A8, A9 Complex) Recombinant Monoclonal Antibody (Product # 6279-RBM5-P1ABX). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          S100A9 + Calprotectin (S100A8/A9 Complex) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          S100A9 + Calprotectin (S100A8/A9 Complex) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          S100A9 + Calprotectin (S100A8/A9 Complex) Antibody in SDS-PAGE (SDS-PAGE)

          Product Details

          6279-RBM5-P1ABX

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Baboon, Bovine, Dog, Horse, Cat, Guinea pig, Goat, Human, Mouse, Non-human primate, Pig, Rabbit, Rat

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          MAC3157R

          Immunogen

          Affinity Purified monocyte membrane preparation

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A/G

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

          Target Information

          The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. The S100A8/A9 complex has antibacterial, antifungal, immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore calprotectin is also detectable in feces. Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: AI323541; B8Ag; BEE11; BEE22; calcium binding protein; S100 protein; calgranulin A; calgranulin B; Calgranulin-A; Calgranulin-B; calprotectin; Calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; Chemotactic cytokine CP-10; chemotactic S100 protein; Cystic fibrosis antigen; intracellular calcium-binding protein (MRP14); Leukocyte L1 complex heavy chain; Leukocyte L1 complex light chain; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; Migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; MRP-14; MRP-8; Myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; Neutrophil cytosolic 7 kDa protein; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; Protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9 (calgranulin B); S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100A8/S100A9; Urinary stone protein band A

          View more View less

          Gene Aliases: 60B8AG; AI323541; AW546964; B8Ag; BEE22; CAGA; CAGB; CFAG; CGLA; CGLB; CP-10; GAGB; L1AG; LIAG; MA387; MAC387; MIF; MRP-14; MRP-8; MRP14; MRP8; NIF; P14; P8; S100A8; S100A9

          View more View less

          UniProt ID: (Bovine) P28782, (Human) P05109, (Bovine) P28783, (Rabbit) P50117, (Human) P06702, (Rat) P50115, (Mouse) P27005, (Mouse) P31725, (Rat) P50116

          View more View less

          Entrez Gene ID: (Guinea pig) 100735514, (Horse) 100061766, (Dog) 490461, (Bovine) 616818, (Pig) 100127488, (Rabbit) 100008985, (Goat) 102168876, (Human) 6279, (Dog) 490463, (Bovine) 532569, (Pig) 100127489, (Horse) 100061730, (Rabbit) 100008704, (Goat) 102182273, (Human) 6280, (Rat) 116547, (Mouse) 20201, (Mouse) 20202, (Guinea pig) 100735238, (Rat) 94195

          View more View less

          Function(s)
          calcium ion binding microtubule binding zinc ion binding antioxidant activity Toll-like receptor 4 binding arachidonic acid binding RAGE receptor binding protein binding signal transducer activity molecular_function metal ion binding calmodulin-related
          Process(es)
          leukocyte migration involved in inflammatory response positive regulation of peptide secretion autophagy apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process astrocyte development peptidyl-cysteine S-nitrosylation neutrophil chemotaxis innate immune response positive regulation of inflammatory response neutrophil aggregation cellular oxidant detoxification positive regulation of intrinsic apoptotic signaling pathway cytokine production acute inflammatory response chronic inflammatory response inflammatory response response to zinc ion positive regulation of cell growth sequestering of zinc ion response to lipopolysaccharide chemokine production wound healing defense response to bacterium response to ethanol defense response to fungus positive regulation of NF-kappaB transcription factor activity regulation of cytoskeleton organization regulation of translation signal transduction cell-cell signaling positive regulation of blood coagulation actin cytoskeleton reorganization peptidyl-cysteine S-trans-nitrosylation regulation of integrin biosynthetic process immune system process chemotaxis regulation of inflammatory response leukocyte chemotaxis
          It has to be done as per old AB suggested Products section.
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