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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 425-454 amino acids from human S6K (RPS6KB1)|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, mouse, rat and rabbit based on sequence homology.
RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
p70 S6 kinase alpha; p70 S6 kinase, alpha; p70(S6K)-alpha; p70-alpha; p70-S6K; P70S6K; ribosomal protein S6 kinase I; ribosomal protein S6 kinase, 70kDa, polypeptide 1; RPS6KB1; S6K; S6K1; serine/threonine kinase 14 alpha; serine/threonine-protein kinase 14A; STK14A
p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; RPS6KB1; S6K; S6K-beta-1; S6K1; STK14A