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FIGURE: 1 / 2
Positive test controls include: 293T, MCF7, DU145, Mouse testis, Mouse thymus, Rat testis. The target is usually found in the following locations: Nucleus.
Immunogen sequence: DSSETTMVKK KVVFCPVKEA LEVDWSSEKA KAALKRTTSD YFLLQVLLKF RTDKGRDPSS DTYEEDSELL LQIRNDVLDS LGISPDLLPE DFVRYCFSEM A
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2. form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999).
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Protein Aliases: activator of SUMO1; FLJ3091; sentrin/SUMO-activating protein AOS1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; ubiquitin-like (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme
Gene Aliases: 2400010M20Rik; 2610044L12Rik; AL033372; AOS1; AW743391; D7Ertd177e; HSPC140; SAE1; SUA1; Ubl1a1; UBLE1A
UniProt ID: (Human) Q9UBE0, (Mouse) Q9R1T2, (Rat) Q6AXQ0
Entrez Gene ID: (Human) 10055, (Mouse) 56459, (Rat) 308384
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