|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant fragment contains a sequence corresponding to a region within amino acids 122 and 451 of SAMHD1|
|Storage buffer||PBS, pH 7|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17280 targets SAMHD1 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-17280 immunogen is recombinant fragment contains a sequence corresponding to a region within amino acids 122 and 451 of SAMHD1.
Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.