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Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COPII-associated small GTPase; SAR1 gene homolog A; SAR1 homolog A; SAR1a gene homolog 1; secretion associated, Ras related GTPase 1A; Secretion-associated Ras-related GTPase 1A; Small COPII coat GTPase SAR1A
Gene Aliases: masra2; SAR1; SAR1A; SARA; SARA1
UniProt ID: (Human) Q9NR31
Entrez Gene ID: (Human) 56681
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