Product References
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.
Nature genetics
Biering SB,Sarnik SA,Wang E,Zengel JR,Leist SR,Schäfer A,Sathyan V,Hawkins P,Okuda K,Tau C,Jangid AR,Duffy CV,Wei J,Gilmore RC,Alfajaro MM,Strine MS,Nguyenla X,Van Dis E,Catamura C,Yamashiro LH,Belk JA,Begeman A,Stark JC,Shon DJ,Fox DM,Ezzatpour S,Huang E,Olegario N,Rustagi A,Volmer AS,Livraghi-Butrico A,Wehri E,Behringer RR,Cheon DJ,Schaletzky J,Aguilar HC,Puschnik AS,Button B,Pinsky BA,Blish CA,Baric RS,O'Neal WK,Bertozzi CR,Wilen CB,Boucher RC,Carette JE,Stanley SA,Harris E,Konermann S,Hsu PD
PA1-41098 was used in Immunohistochemistry to conclude that this functional landscape of SARS-CoV-2 host factors provides a physiologically relevant starting point for new host-directed therapeutics and highlights airway mucins as a host defense mechanism.
Mon Aug 01 00:00:00 EDT 2022
KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney.
medRxiv : the preprint server for health sciences
Mori Y,Fink C,Ichimura T,Sako K,Mori M,Lee NN,Aschauer P,Padmanabha Das KM,Hong S,Song M,Padera RF,Weins A,Lee LP,Nasr ML,Dekaban GA,Dikeakos JD,Bonventre JV
PA1-41098 was used in Immunocytochemistry to show that KIM-1 acts as a receptor for SARS-CoV-2 both in lung and kidney epithelia.
Tue Jan 11 00:00:00 EST 2022
SARS-CoV-2 infection of the oral cavity and saliva.
Nature medicine
Huang N,Pérez P,Kato T,Mikami Y,Okuda K,Gilmore RC,Conde CD,Gasmi B,Stein S,Beach M,Pelayo E,Maldonado JO,Lafont BA,Jang SI,Nasir N,Padilla RJ,Murrah VA,Maile R,Lovell W,Wallet SM,Bowman NM,Meinig SL,Wolfgang MC,Choudhury SN,Novotny M,Aevermann BD,Scheuermann RH,Cannon G,Anderson CW,Lee RE,Marchesan JT,Bush M,Freire M,Kimple AJ,Herr DL,Rabin J,Grazioli A,Das S,French BN,Pranzatelli T,Chiorini JA,Kleiner DE,Pittaluga S,Hewitt SM,Burbelo PD,Chertow D,Frank K,Lee J,Boucher RC,Teichmann SA,Warner BM,Byrd KM
PA1-41098 was used in Immunohistochemistry to show that the oral cavity is an important site for SARS-CoV-2 infection and implicate saliva as a potential route of SARS-CoV-2 transmission.
Sat May 01 00:00:00 EDT 2021
Broad-Spectrum Antiviral Activity of 3D8, a Nucleic Acid-Hydrolyzing Single-Chain Variable Fragment (scFv), Targeting SARS-CoV-2 and Multiple Coronaviruses In Vitro.
Viruses
Lee G,Budhathoki S,Lee GY,Oh KJ,Ham YK,Kim YJ,Lim YR,Hoang PT,Lee Y,Lim SW,Kim JM,Cho S,Kim TH,Song JW,Lee S,Kim WK
Published figure using SARS Coronavirus Nucleocapsid polyclonal antibody (Product # PA1-41098) in Western Blot
Fri Apr 09 00:00:00 EDT 2021
Experimental Susceptibility of North American Raccoons (Procyon lotor) and Striped Skunks (Mephitis mephitis) to SARS-CoV-2.
Frontiers in veterinary science
Francisco R,Hernandez SM,Mead DG,Adcock KG,Burke SC,Nemeth NM,Yabsley MJ
PA1-41098 was used in Immunohistochemistry to show that continued outbreaks in non-domestic species, wild and captive, highlight that additional research on the susceptibility of SARS-CoV-2 in wildlife, especially musteloidea, and of conservation concern, is needed.
Sun Nov 05 00:00:00 EDT 2023
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice.
Cell
Leist SR,Dinnon KH,Schäfer A,Tse LV,Okuda K,Hou YJ,West A,Edwards CE,Sanders W,Fritch EJ,Gully KL,Scobey T,Brown AJ,Sheahan TP,Moorman NJ,Boucher RC,Gralinski LE,Montgomery SA,Baric RS
PA1-41098 was used in Immunohistochemistry to generate a new mouse-adapted SARS-CoV-2 virus that induces aspects of severe COVID-19 disease, such as acute lung injury and mortality, in standard laboratory mice.
Thu Nov 12 00:00:00 EST 2020
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.
Cell
Hou YJ,Okuda K,Edwards CE,Martinez DR,Asakura T,Dinnon KH,Kato T,Lee RE,Yount BL,Mascenik TM,Chen G,Olivier KN,Ghio A,Tse LV,Leist SR,Gralinski LE,Schäfer A,Dang H,Gilmore R,Nakano S,Sun L,Fulcher ML,Livraghi-Butrico A,Nicely NI,Cameron M,Cameron C,Kelvin DJ,de Silva A,Margolis DM,Markmann A,Bartelt L,Zumwalt R,Martinez FJ,Salvatore SP,Borczuk A,Tata PR,Sontake V,Kimple A,Jaspers I,O'Neal WK,Randell SH,Boucher RC,Baric RS
PA1-41098 was used in Immunocytochemistry-immunoflourescence to highlight the nasal susceptibility to SARS-CoV-2 with likely subsequent aspiration-mediated virus seeding to the lung in SARS-CoV-2 pathogenesis.
Thu Jul 23 00:00:00 EDT 2020
Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.
Cell stem cell
Katsura H,Sontake V,Tata A,Kobayashi Y,Edwards CE,Heaton BE,Konkimalla A,Asakura T,Mikami Y,Fritch EJ,Lee PJ,Heaton NS,Boucher RC,Randell SH,Baric RS,Tata PR
Published figure using SARS Coronavirus Nucleocapsid polyclonal antibody (Product # PA1-41098) in Immunohistochemistry
Thu Dec 03 00:00:00 EST 2020
Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.
Cell stem cell
Katsura H,Sontake V,Tata A,Kobayashi Y,Edwards CE,Heaton BE,Konkimalla A,Asakura T,Mikami Y,Fritch EJ,Lee PJ,Heaton NS,Boucher RC,Randell SH,Baric RS,Tata PR
Published figure using SARS Coronavirus Nucleocapsid polyclonal antibody (Product # PA1-41098) in Immunohistochemistry
Thu Dec 03 00:00:00 EST 2020
Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients.
Critical care (London, England)
Remmelink M,De Mendonça R,D'Haene N,De Clercq S,Verocq C,Lebrun L,Lavis P,Racu ML,Trépant AL,Maris C,Rorive S,Goffard JC,De Witte O,Peluso L,Vincent JL,Decaestecker C,Taccone FS,Salmon I
Published figure using SARS Coronavirus Nucleocapsid polyclonal antibody (Product # PA1-41098) in Immunohistochemistry
Wed Aug 12 00:00:00 EDT 2020
Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients.
Critical care (London, England)
Remmelink M,De Mendonça R,D'Haene N,De Clercq S,Verocq C,Lebrun L,Lavis P,Racu ML,Trépant AL,Maris C,Rorive S,Goffard JC,De Witte O,Peluso L,Vincent JL,Decaestecker C,Taccone FS,Salmon I
Published figure using SARS Coronavirus Nucleocapsid polyclonal antibody (Product # PA1-41098) in Immunohistochemistry
Wed Aug 12 00:00:00 EDT 2020
SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo.
bioRxiv : the preprint server for biology
Hou YJ,Chiba S,Halfmann P,Ehre C,Kuroda M,Dinnon KH,Leist SR,Schäfer A,Nakajima N,Takahashi K,Lee RE,Mascenik TM,Edwards CE,Tse LV,Boucher RC,Randell SH,Suzuki T,Gralinski LE,Kawaoka Y,Baric RS
PA1-41098 was used in Immunocytochemistry to demonstrate the SARS-CoV2 D614G substitution enhances infectivity, replication fitness, and early transmission.
Tue Sep 29 00:00:00 EDT 2020
SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo.
bioRxiv : the preprint server for biology
Hou YJ,Chiba S,Halfmann P,Ehre C,Kuroda M,Dinnon KH,Leist SR,Schäfer A,Nakajima N,Takahashi K,Lee RE,Mascenik TM,Edwards CE,Tse LV,Boucher RC,Randell SH,Suzuki T,Gralinski LE,Kawaoka Y,Baric RS
PA1-41098 was used in Immunocytochemistry to demonstrate the SARS-CoV2 D614G substitution enhances infectivity, replication fitness, and early transmission.
Tue Sep 29 00:00:00 EDT 2020
Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis.
medRxiv : the preprint server for health sciences
Huang N,Perez P,Kato T,Mikami Y,Okuda K,Gilmore RC,Domínguez Conde C,Gasmi B,Stein S,Beach M,Pelayo E,Maldonado J,LaFont B,Padilla R,Murrah V,Maile R,Lovell W,Wallet S,Bowman NM,Meinig SL,Wolfgang MC,Choudhury SN,Novotny M,Aevermann BD,Scheuermann R,Cannon G,Anderson C,Marchesan J,Bush M,Freire M,Kimple A,Herr DL,Rabin J,Grazioli A,French BN,Pranzatelli T,Chiorini JA,Kleiner DE,Pittaluga S,Hewitt S,Burbelo PD,Chertow D,Frank K,Lee J,Boucher RC,Teichmann SA,Warner BM,Byrd KM
PA1-41098 was used in Immunocytochemistry to investigate the involvement of the oral cavity in COVID-19.
Tue Oct 27 00:00:00 EDT 2020