Product References
Reversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers.
Materials today. Bio
Dabrowska A,Botwina P,Barreto-Duran E,Kubisiak A,Obloza M,Synowiec A,Szczepanski A,Targosz-Korecka M,Szczubialka K,Nowakowska M,Pyrc K
MA5-29981 was used in Immunocytochemistry-immunofluorescence to assess the efficacy and underlying mechanism of the inhibitors using fully differentiated human airway epithelial cultures, wherein near-complete abrogation of viral replication was documented.
Sun Oct 01 00:00:00 EDT 2023
Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response.
iScience
Wang Y,Li P,Xu L,de Vries AC,Rottier RJ,Wang W,Crombag MBS,Peppelenbosch MP,Kainov DE,Pan Q
MA5-29981 was used in Immunocytochemistry-immunofluorescence to demostrate that indomethacin is a pan-coronavirus inhibitor that can simultaneously inhibit virus-triggered inflammatory response.
Fri Sep 15 00:00:00 EDT 2023
Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2.
Viruses
Diallo I,Jacob RA,Vion E,Kozak RA,Mossman K,Provost P
MA5-29981 was used in Western Blotting to highlight the modulatory role of miRNAs in the pathogenesis of SARS-CoV-2.
Fri Feb 10 00:00:00 EST 2023
Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.
ACS infectious diseases
Pohl MO,Martin-Sancho L,Ratnayake R,White KM,Riva L,Chen QY,Lieber G,Busnadiego I,Yin X,Lin S,Pu Y,Pache L,Rosales R,Déjosez M,Qin Y,De Jesus PD,Beall A,Yoh S,Hale BG,Zwaka TP,Matsunaga N,García-Sastre A,Stertz S,Chanda SK,Luesch H
Published figure using SARS/SARS-CoV-2 Nucleocapsid monoclonal antibody (Product # MA5-29981) in Immunocytochemistry
Fri Jul 08 00:00:00 EDT 2022
Mechanism of Multi-Organ Injury in Experimental COVID-19 and Its Inhibition by a Small Molecule Peptide.
Frontiers in pharmacology
Paidas MJ,Sampath N,Schindler EA,Cosio DS,Ndubizu CO,Shamaladevi N,Kwal J,Rodriguez S,Ahmad A,Kenyon NS,Jayakumar AR
MA5-29981 was used in Immunohistochemistry (Paraffin) to suggest the possible involvement of altered aquaporins and the subsequent edema, likely mediated by the virus-induced inflammatory and oxidative stress response, in the pathogenesis of COVID- 19 and the potential of SPIKENET as a therapeutic option.
Sat Jul 16 00:00:00 EDT 2022
SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis.
iScience
Szlachcic WJ,Dabrowska A,Milewska A,Ziojla N,Blaszczyk K,Barreto-Duran E,Sanak M,Surmiak M,Owczarek K,Grzanka D,Durzynska J,Pyrc K,Borowiak M
MA5-29981 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to investigate whether SARS-CoV-2 infection may affect pancreas development, possibly causing lifelong health consequences.
Fri Jul 15 00:00:00 EDT 2022
Differential neutralization and inhibition of SARS-CoV-2 variants by antibodies elicited by COVID-19 mRNA vaccines.
Nature communications
Wang L,Kainulainen MH,Jiang N,Di H,Bonenfant G,Mills L,Currier M,Shrivastava-Ranjan P,Calderon BM,Sheth M,Mann BR,Hossain J,Lin X,Lester S,Pusch EA,Jones J,Cui D,Chatterjee P,Jenks MH,Morantz EK,Larson GP,Hatta M,Harcourt JL,Tamin A,Li Y,Tao Y,Zhao K,Lacek K,Burroughs A,Wang W,Wilson M,Wong T,Park SH,Tong S,Barnes JR,Tenforde MW,Self WH,Shapiro NI,Exline MC,Files DC,Gibbs KW,Hager DN,Patel M,Halpin AL,McMullan LK,Lee JS,Xia H,Xie X,Shi PY,Davis CT,Spiropoulou CF,Thornburg NJ,Oberste MS,Dugan VG,Wentworth DE,Zhou B
MA5-29981 was used in Immunocytochemistry-immunoflourescence to conclude that vaccination remains an effective strategy during the COVID-19 pandemic.
Wed Jul 27 00:00:00 EDT 2022
Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways.
iScience
Richard D,Muthuirulan P,Aguiar J,Doxey AC,Banerjee A,Mossman K,Hirota J,Capellini TD
MA5-29981 was used in Western Blotting to study the mechanisms of ACE2 regulation and the response to immune signaling and oxidative-stress pathways.
Fri Jul 15 00:00:00 EDT 2022
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models.
Science translational medicine
Hajnik RL,Plante JA,Liang Y,Alameh MG,Tang J,Bonam SR,Zhong C,Adam A,Scharton D,Rafael GH,Liu Y,Hazell NC,Sun J,Soong L,Shi PY,Wang T,Walker DH,Sun J,Weissman D,Weaver SC,Plante KS,Hu H
MA5-29981 was used in Western Blotting to suggest that combined mRNA-S+N vaccination is an effective approach for promoting broad protection against SARS-CoV-2 variants.
Wed Sep 14 00:00:00 EDT 2022
Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies.
NPJ vaccines
Zhong C,Xia H,Adam A,Wang B,Hajnik RL,Liang Y,Rafael GH,Zou J,Wang X,Sun J,Soong L,Barrett ADT,Weaver SC,Shi PY,Wang T,Hu H
Published figure using SARS/SARS-CoV-2 Nucleocapsid monoclonal antibody (Product # MA5-29981) in Western Blot
Mon Nov 29 00:00:00 EST 2021
Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies.
NPJ vaccines
Zhong C,Xia H,Adam A,Wang B,Hajnik RL,Liang Y,Rafael GH,Zou J,Wang X,Sun J,Soong L,Barrett ADT,Weaver SC,Shi PY,Wang T,Hu H
Published figure using SARS/SARS-CoV-2 Nucleocapsid monoclonal antibody (Product # MA5-29981) in Western Blot
Mon Nov 29 00:00:00 EST 2021
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Nature communications
Kruse T,Benz C,Garvanska DH,Lindqvist R,Mihalic F,Coscia F,Inturi R,Sayadi A,Simonetti L,Nilsson E,Ali M,Kliche J,Moliner Morro A,Mund A,Andersson E,McInerney G,Mann M,Jemth P,Davey NE,Överby AK,Nilsson J,Ivarsson Y
MA5-29981 was used in Western Blot to describe a viral peptide discovery approach covering 23 coronavirus strains that provides high resolution information on direct virus-host interactions.
Fri Nov 19 00:00:00 EST 2021
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Nature communications
Kruse T,Benz C,Garvanska DH,Lindqvist R,Mihalic F,Coscia F,Inturi R,Sayadi A,Simonetti L,Nilsson E,Ali M,Kliche J,Moliner Morro A,Mund A,Andersson E,McInerney G,Mann M,Jemth P,Davey NE,Överby AK,Nilsson J,Ivarsson Y
MA5-29981 was used in Western Blot to describe a viral peptide discovery approach covering 23 coronavirus strains that provides high resolution information on direct virus-host interactions.
Fri Nov 19 00:00:00 EST 2021
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.
Cell reports
Pablos I,Machado Y,de Jesus HCR,Mohamud Y,Kappelhoff R,Lindskog C,Vlok M,Bell PA,Butler GS,Grin PM,Cao QT,Nguyen JP,Solis N,Abbina S,Rut W,Vederas JC,Szekely L,Szakos A,Drag M,Kizhakkedathu JN,Mossman K,Hirota JA,Jan E,Luo H,Banerjee A,Overall CM
Published figure using SARS/SARS-CoV-2 Nucleocapsid monoclonal antibody (Product # MA5-29981) in Western Blot
Tue Oct 26 00:00:00 EDT 2021
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses.
iScience
Banerjee A,El-Sayes N,Budylowski P,Jacob RA,Richard D,Maan H,Aguiar JA,Demian WL,Baid K,D'Agostino MR,Ang JC,Murdza T,Tremblay BJ,Afkhami S,Karimzadeh M,Irving AT,Yip L,Ostrowski M,Hirota JA,Kozak R,Capellini TD,Miller MS,Wang B,Mubareka S,McGeer AJ,McArthur AG,Doxey AC,Mossman K
MA5-29981 was used in Immunocytochemistry, Western Blot to demonstrate that SARS-CoV-2 infection induces a type I IFN response in vitro and in moderate cases of COVID-19.
Fri May 21 00:00:00 EDT 2021
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses.
iScience
Banerjee A,El-Sayes N,Budylowski P,Jacob RA,Richard D,Maan H,Aguiar JA,Demian WL,Baid K,D'Agostino MR,Ang JC,Murdza T,Tremblay BJ,Afkhami S,Karimzadeh M,Irving AT,Yip L,Ostrowski M,Hirota JA,Kozak R,Capellini TD,Miller MS,Wang B,Mubareka S,McGeer AJ,McArthur AG,Doxey AC,Mossman K
MA5-29981 was used in Immunocytochemistry, Western Blot to demonstrate that SARS-CoV-2 infection induces a type I IFN response in vitro and in moderate cases of COVID-19.
Fri May 21 00:00:00 EDT 2021