Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.
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Protein Aliases: DNA-binding protein SATB2; KIAA1034-like DNA binding protein; SATB family member 2; special AT-rich sequence binding protein 2; Special AT-rich sequence-binding protein 2; two cut domains-containing homeodomain protein
Gene Aliases: GLSS; KIAA1034; mKIAA1034; RGD1562369; SATB2