Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product # 7KMWCO
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen-like 1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; scavenger receptor b1; Scavenger receptor class B member 1; scavenger receptor class B type III; scavenger receptor class B, member 1; SR-BI; SRB1
Gene Aliases: CD36L1; CLA-1; CLA1; HDLQTL6; SCARB1; SR-BI; SRB1
UniProt ID: (Human) Q8WTV0
Entrez Gene ID: (Human) 949
Molecular Function: receptor