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The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
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Protein Aliases: Chromogranin-C; Secretogranin II; Secretogranin-2; secretoneurin; SgII
Gene Aliases: CHGC; EM66; SCG2; SgII; SN
UniProt ID: (Human) P13521
Entrez Gene ID: (Human) 7857
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