|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human SDCG1|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Nuclear export mediator factor, NEMF, plays a role in nuclear export. It is expressed in brain, heart, liver, lung, spleen, and skeletal muscle tissue, and expressed at lower levels in stomach and testis. It interacts (via its N-terminus) with XPO1; the N-terminal domain contains a nuclear export signal and the C-terminal domain may interact with cargo proteins. This protein is active in normal lung tissue but is inactive in several lung cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.