Applications | Tested Dilution | Publications |
---|---|---|
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
5E10G12 |
Immunogen |
Recombinant Protein |
Conjugate |
CoraLite®594
|
Form |
Liquid |
Concentration |
2 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.3, with 0.5% BSA, 50% glycerol |
Contains |
0.05% Proclin 300 |
Storage conditions |
-20° C, store in dark |
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Flavoprotein subunit of complex II; Fp; succinate dehydrogenase [ubiquinone] flavoprotein subunit; Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; succinate dehydrogenase complex subunit A, flavoprotein (Fp); succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Gene Aliases: 1500032O14Rik; 2310034D06Rik; 4921513A11; C81073; CMD1GG; FP; PGL5; SDH1; SDH2; SDHA; SDHF
UniProt ID: (Human) P31040, (Rat) Q920L2, (Mouse) Q8K2B3
Entrez Gene ID: (Human) 6389, (Rat) 157074, (Mouse) 66945
Molecular Function:
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
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