Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SEC14-like protein 1
Gene Aliases: PRELID4A; SEC14L; SEC14L1
UniProt ID: (Human) Q92503
Entrez Gene ID: (Human) 6397
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