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Invitrogen
SEC61alpha Recombinant Rabbit Monoclonal Antibody (ARC2323)
FIGURE: 1 / 1
SEC61alpha Antibody (MA5-38005) in WB
Western blot analysis of SEC61alpha in extracts of various cell lines. Samples were incubated with SEC61alpha Monoclonal antibody (Product # MA5-38005) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
MA5-38005
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC2323
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Sec61A (Q9H9S3)
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897923
Product Specific Information
Positive Samples: 293T, SH-SY5Y, Mouse lung, Mouse testis, Mouse brain, Rat testis
Immunogen sequence: SMGAIFEDPV HVVVYIIFML GSCAFFSKTW IEVSGSSAKD VAKQLKEQQM VMRGHRDTSM VHELNRYIPT AAAFGGLCIG ALSVLADFLG AIGSGTGILL A
Target Information
The SEC61 complex is a major component of the endoplasmic reticulum (ER) translocation site. This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: protein transport protein Sec61 subunit alpha; Protein transport protein Sec61 subunit alpha isoform 2; Sec61 alpha; Sec61 alpha 2 subunit; Sec61 alpha form 2; Sec61 alpha-2; Sec61, alpha subunit 2
Gene Aliases: SEC61A2
UniProt ID: (Human) Q9H9S3, (Mouse) Q9JLR1
Entrez Gene ID: (Human) 55176, (Rat) 361273, (Mouse) 57743
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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