OriGene

SELENBP1 Monoclonal Antibody (OTI3H1), TrueMAB™

Advanced Verification

This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.

View all (25) SELENBP1 antibodies

Datasheet

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Datasheet

Protocols

Questions & Answers

Tech Support

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SELENBP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of paraffin-embedded human lymph node tissue within the normal limits using anti-SELENBP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, TA504701)

SELENBP1 Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SELENBP1 (RC202108, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SEL. Positive lysates LY401295 (100 µg) and LC401295 (20 µg) can be purchased separately from OriGene.

SELENBP1 Antibody — Antibody specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. Loss of signal was observed for target protein in SELENBP1 knockout (KO) HeLa cell line using Anti-SELENBP1 monoclonal antibody (Product # CF504701). {KO}

Product Details

CF504701

Applications	Tested Dilution	Publications
Western Blot (WB)	1:2,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:150	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Mouse / IgG2a
Class	Monoclonal
Type	Antibody
Clone	OTI3H1
Immunogen	Full length human recombinant protein of human SELENB1 produced in HEK293T cell. View antigen
Conjugate	Unconjugated
Form	lyophilized
Concentration	1 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.3, with 8% trehalose
Contains	no preservative
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 56 kDa selenium-binding protein; epididymis secretory sperm binding protein Li 134P; FLJ13813; hSP56; Lp 56; Methanethiol oxidase; MTO; SBP 1; SBP56; Selen bp2; SELENBP 1; Selenbp 2; Selenium-binding protein 1; SELNBP1; SP 56; SP56

Gene Aliases: HEL-S-134P; hSBP; Lp56; LPSB; SBP; SBP56; SELENBP1; SP56

UniProt ID: (Human) Q13228, (Mouse) P17563

Entrez Gene ID: (Human) 8991, (Mouse) 20341

Molecular Function: defense/immunity protein