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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1D5G8 |
Immunogen |
Purified recombinant fragment of human CD108 (aa: 48-222) expressed in E. Coli. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS |
Contains |
0.05% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
This antibody has been tested in indirect ELISA.
CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and beta1 integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD108; CDw108; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; John-Milton-Hargen human blood group Ag; MGC126692; MGC126696; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; Sema K1; Sema L; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin-7A; Semaphorin-K1; Semaphorin-L
Gene Aliases: CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; SEMA7A; SEMAK1; SEMAL
UniProt ID: (Human) O75326
Entrez Gene ID: (Human) 8482
Molecular Function:
membrane-bound signaling molecule
intercellular signal molecule
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