|Tested species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 101 and 347 of Human SEPT3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA5-31124 targets SEPT3 in WB applications and shows reactivity with Human and mouse samples.
The PA5-31124 immunogen is recombinant fragment corresponding to a region within amino acids 101 and 347 of Human SEPT3.
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Cell type-specific expression of SEPT3-homology subgroup members controls the subunit number of heteromeric septin complexes.
PA5-31124 was used in western blot to determine SEPT3-homology and cell type-specific expression and how it controls the subunit number of heteromeric septin complexes
|Sellin ME,Stenmark S,Gullberg M||Molecular biology of the cell (25:1594)||2014|